Primary Pulmonary Ewing's Sarcoma/Primitive Neuroectodermal Tumor in a 67-year-old Man

نویسندگان

  • Yoon Young Lee
  • Do Hoon Kim
  • Ji Hye Lee
  • Jong Sang Choi
  • Kwang Ho In
  • Yu Whan Oh
  • Kyung Hwan Cho
  • Yong Kyun Roh
چکیده

Extraskeletal Ewing's sarcoma (EES) is a branch of neuroectodermal tumor (PNET), which is very rare soft tissue sarcoma. We report a case of EES/PNET arising is the lung of a 67-yr-old man. Computed tomography, bone scintigraphy, and positron emission tomography confirmed the mass to have a primary pulmonary origin. The mass showed positive reactivity in the Periodic Acid Schiff (PAS) stain and MIC-2 immunoreactivity in immunohistochemical stain. Fluorescence in situ hybridization (FISH) was performed, which revealed an EWSR1 (Ewing sarcoma breakpoint region 1) 22q12 rearrangement. The diagnosis was confirmed both pathologically and genetically. The mass lesion was resected, and the patient is currently undergoing chemotherapy.

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عنوان ژورنال:

دوره 22  شماره 

صفحات  -

تاریخ انتشار 2007